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The Yale Global Health Leadership Initiative has been awarded a highly competitive research grant of more than $1 million to address sepsis care and reduce inequities among African American/Black and Latinx communities.
The R01 grant was awarded by National Institute of General Medical Studies, Department of National Institutes of Health. Promoting health equity and social justice is one of the core values ​​of the Yale School of Public Health. A detailed description of the novel research initiative is presented BMC Health Services Research.
Sepsis is a life-threatening health problem that occurs when the body’s immune system reacts to an infection. In the US, African American/Black and Latinx sepsis have higher complication rates, disparities in standard care and readmissions compared to non-Hispanic white populations, the researchers said.
The purpose of the funded research is to develop and evaluate a cohort-based leadership intervention that will help eight US hospital systems and their surrounding communities address structural racism and achieve measurable reductions in inequities in sepsis care and outcomes, said director Erica Leander. Global Health Leadership Initiative and one of the principal investigators for the project.
“Any complex health outcome that requires the coordination of different parts of the health care system is perfect for intervention in leadership and organizational culture,” said Linder. “There is a need to develop a culture where people come together and become problem solvers around these complex issues, especially issues related to racism.”
Over the next three years, the researchers will develop and test an intervention using quantitative and qualitative data analysis to observe changes in organizational culture. The team then examines the impact of a change in organizational culture on reducing sepsis-related racial inequities by focusing on three outcomes: early detection and treatment, readmission, and mortality.
Other principal investigators for the study are Professor Leslie Currie of the Yale School of Health and Dr. Dowin Boatwright, assistant professor of emergency medicine at the Yale School of Medicine.
R01 research grant honors are subject to a rigorous application process. Leander credits a new internal peer review process implemented by Melinda Irwin, associate dean of the Yale School of Public Health, for the team’s success in its first grant application.
“Our first draft of the application was greatly strengthened by the critical review of our peers, which helped us identify proposals that needed more in-depth explanation,” Leander said.
Carrie agreed. “The reviews, especially taken together, provided very valuable criticism and constructive suggestions for refinement. We’ve taken every comment into account. “
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